S3386
山梨糖醇酐倍半油酸酯
nonionic surfactant
别名:
Arlacel® 83, Span® 83
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化学文摘社编号:
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
232-360-1
MDL number:
产品名称
山梨糖醇酐倍半油酸酯, nonionic surfactant
InChI key
SPFRYHCSFBFNTR-RKGWDQTMSA-N
InChI
1S/3C18H34O2.2C6H12O5/c3*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;2*7-1-3(8)6-5(10)4(9)2-11-6/h3*9-10H,2-8,11-17H2,1H3,(H,19,20);2*3-10H,1-2H2/b3*10-9-;;/t;;;2*3-,4+,5-,6-/m...11/s1
SMILES string
OC[C@@H](O)C1OC[C@H](O)[C@H]1O.OC[C@@H](O)C2OC[C@H](O)[C@H]2O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O
biological source
corn
vapor pressure
0.81 psi ( 20 °C)
form
liquid
refractive index
n20/D 1.478 (lit.)
density
0.989 g/mL at 25 °C (lit.)
functional group
ester
lipid type
oils
shipped in
ambient
storage temp.
room temp
Quality Level
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Biochem/physiol Actions
倍半油酸山梨坦在生产球形丙烯酰胺微珠的聚合过程中可用作稳定剂。它已被用于许多外用药物。 最近发现SSO与过敏性皮炎有关。
General description
倍半油酸山梨坦(SSO) 是一种山梨醇衍生物乳化剂。它是外用皮质类固醇、外用抗生素、外用抗真菌剂、保湿霜和乳液以及外用维A酸中的常见乳化剂成分。
Other Notes
脂肪酸组成：油酸（C18:1）约70%；主要用于平衡的棕榈酸（C16:0）、硬脂酸（C18:0）和亚油酸（C18:2）。
Legal Information
Arlacel is a registered trademark of Croda International PLC
Span is a registered trademark of Croda International PLC
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Adam Asarch et al.
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In the past, sorbitan sesquioleate (SSO) was reported as an uncommon allergen, but recent data suggest SSO may be an important sensitizer. To present data on 13 of 112 dermatitis patients who reacted to SSO and/or sorbitan monooleate (SMO) on
Allergic contact dermatitis to sorbitan sesquioleate in Adaptic wound dressing.
F B de Waard-van der Spek et al.
Contact dermatitis, 57(1), 54-56 (2007-06-20)
Contact dermatitis due to emulsifiers.
F Pereira et al.
Contact dermatitis, 36(2), 114-114 (1997-02-01)
Contact urticaria syndrome from sorbitan sesquioleate in a corticosteroid ointment.
M Hardy et al.
Contact dermatitis, 32(6), 360-361 (1995-06-01)
The Validity of Patch Testing
Lachapelle JM, et al.
Patch Testing Tips, 49(4), 37-61 (2014)
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