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Merck
CN

S3388

Sigma-Aldrich

磺基罗丹明101 酸氯

Technical grade

别名:

磺基罗丹明101磺酰氯

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关于此项目

经验公式（希尔记法）:
C31H29ClN2O6S2
化学文摘社编号:
82354-19-6
分子量:
625.15
Beilstein:
8667894
MDL编号:
MFCD00012406
UNSPSC代码:
12171500
PubChem化学物质编号:
24899558
NACRES:
NA.47

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表单

powder

组成

Dye content, ~75%

杂质

~1 mol/mol chloroform as solvent of crystallization

溶解性

methanol: 10 mg/mL

荧光

λex 586 nm; λem 605 nm in H2O

应用

diagnostic assay manufacturing
hematology
histology

储存温度

−20°C

SMILES字符串

[O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O

InChI

1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2

InChI key

MPLHNVLQVRSVEE-UHFFFAOYSA-N

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一般描述

磺酰罗丹明101是一种红色荧光染料，是水溶性的两性罗丹明。该染料可专门用作新皮质中星形胶质细胞的标记。常用于大脑成像。研究表明磺酰罗丹明101可用作癫痫引发药物。

应用

酸性桃红 101 酰氯已被用于封装的荧光探针中，作为模型药物研究基于鼠李糖半乳糖醛酸-I 的微胶囊的药物递送特性。它还作为星形胶质细胞特异性染料，用于共聚焦成像。

其他说明

酸性桃红 101 的两种单磺酰氯衍生物的混合物。

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险分类

Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

易制毒化学品（2类）
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
068K3799
058K3784
038K3776
028K1387
117K3780

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Jorge O Escobedo et al.
Natural product communications, 7(3), 317-320 (2012-05-02)
Understanding cellular mechanisms of ototoxic and nephrotoxic drug uptake, intracellular distribution, and molecular trafficking across cellular barrier systems aids the study of potential uptake blockers that preserve sensory and renal function during critical life-saving therapy. Herein we report the design
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Biomacromolecules, 13(5), 1383-1389 (2012-04-05)
We developed a facile and quick ethanol-based method for preparing silk nanoparticles and then fabricated a biodegradable and biocompatible dual-drug release system based on silk nanoparticles and the molecular networks of silk hydrogels. Model drugs incorporated in the silk nanoparticles
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo.
Nimmerjahn A
Nature Materials, 1(1), 31-37 (2004)
Sara Seabrooke et al.
The Journal of experimental biology, 215(Pt 17), 2945-2949 (2012-08-10)
We describe a method for calculating rates of fluorochrome transport from unstirred layer (USL) concentration gradients measured using confocal microscopy. Isolated Malpighian tubules or guts of Drosophila melanogaster were secured to depression slides and bathed in saline containing a fluorescent
Yang Liu et al.
Pharmaceutical research, 29(12), 3273-3277 (2012-07-19)
The biodistribution of Lipid/Calcium/Phosphate (LCP) nanoparticles (NPs) in tumor-bearing mice was investigated using fluorescence imaging. A quantitative validation of this method was done by (3)H and (111)In labeling of the nanoparticles. The biodistribution of LCP NPs containing oligonucleotides was investigated
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