S3388

磺基罗丹明101 酸氯

Name: 磺基罗丹明101 酸氯
Brand: SIGMA

Technical grade

别名:

磺基罗丹明101磺酰氯

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经验公式（希尔记法）:

C₃₁H₂₉ClN₂O₆S₂

化学文摘社编号:

82354-19-6

分子量:

625.15

UNSPSC Code:

12171500

NACRES:

NA.47

PubChem Substance ID:

24899558

MDL number:

MFCD00012406

Beilstein/REAXYS Number:

8667894

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产品名称

磺基罗丹明101 酸氯, Technical grade

InChI

1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2

SMILES string

[O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O

InChI key

MPLHNVLQVRSVEE-UHFFFAOYSA-N

form

powder

composition

Dye content, ~75%

impurities

~1 mol/mol chloroform as solvent of crystallization

solubility

methanol: 10 mg/mL

fluorescence

λ_ex 586 nm; λ_em 605 nm in H₂O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

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Other Notes

酸性桃红 101 的两种单磺酰氯衍生物的混合物。

Application

酸性桃红 101 酰氯已被用于封装的荧光探针中，作为模型药物研究基于鼠李糖半乳糖醛酸-I 的微胶囊的药物递送特性。它还作为星形胶质细胞特异性染料，用于共聚焦成像。

General description

磺酰罗丹明101是一种红色荧光染料，是水溶性的两性罗丹明。该染料可专门用作新皮质中星形胶质细胞的标记。常用于大脑成像。研究表明磺酰罗丹明101可用作癫痫引发药物。

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H315,H319,H351,H361d,H372

pcodes

P201 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

易制毒化学品（2类）

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Distribution of gentamicin in inner ear after local administration via a chitosan glycerophosphate hydrogel delivery system.

Jianfen Luo et al.

The Annals of otology, rhinology, and laryngology, 121(3), 208-216 (2012-04-26)

We examined the distribution of gentamicin sulfate in the inner ear after delivery via a chitosan glycerophosphate (CGP) hydrogel system and examined the change in morphology of the hair cells so as to determine how gentamicin affected the function of

Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis

Mona S

Scientific Reports, 63, 33249-33249 (2016)

Rhamnogalacturonan-I Based Microcapsules for Targeted Drug Release

Anna J

PLoS ONE, 11(12), e0168050-e0168050 (2016)

In vivo imaging of oligodendrocytes with sulforhodamine 101

Robert A Hill

Nature Medicine, 11(11), 1081-1082 (2014)

Bumetanide hyperpolarizes madin-darby canine kidney cells and enhances cellular gentamicin uptake by elevating cytosolic Ca(2+) thus facilitating intermediate conductance Ca(2+)--activated potassium channels.

Tian Wang et al.

Cell biochemistry and biophysics, 65(3), 381-398 (2012-10-31)

Loop diuretics such as bumetanide and furosemide enhance aminoglycoside ototoxicity when co-administered to patients and animal models. The underlying mechanism(s) is poorly understood. We investigated the effect of these diuretics on cellular uptake of aminoglycosides, using Texas Red-tagged gentamicin (GTTR)

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磺基罗丹明101 酸氯

Technical grade

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关于此项目

主要文件

属性

产品名称

InChI

SMILES string

InChI key

form

composition

impurities

solubility

fluorescence

application(s)

storage temp.

说明

Other Notes

Application

General description

安全信息

pictograms

signalword

hcodes

pcodes

Hazard Classifications

存储类别

wgk

flash_point_f

flash_point_c

法规信息

文件

分析证书(COA)

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