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Merck
CN

S3388

磺基罗丹明101 酸氯

Technical grade

别名:

磺基罗丹明101磺酰氯

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关于此项目

经验公式（希尔记法）:
C31H29ClN2O6S2
化学文摘社编号:
82354-19-6
分子量:
625.15
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24899558
MDL number:
MFCD00012406
Beilstein/REAXYS Number:
8667894

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InChI

1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2

SMILES string

[O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O

InChI key

MPLHNVLQVRSVEE-UHFFFAOYSA-N

form

powder

composition

Dye content, ~75%

impurities

~1 mol/mol chloroform as solvent of crystallization

solubility

methanol: 10 mg/mL

fluorescence

λex 586 nm; λem 605 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

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General description

磺酰罗丹明101是一种红色荧光染料，是水溶性的两性罗丹明。该染料可专门用作新皮质中星形胶质细胞的标记。常用于大脑成像。研究表明磺酰罗丹明101可用作癫痫引发药物。

Application

酸性桃红 101 酰氯已被用于封装的荧光探针中，作为模型药物研究基于鼠李糖半乳糖醛酸-I 的微胶囊的药物递送特性。它还作为星形胶质细胞特异性染料，用于共聚焦成像。

Other Notes

酸性桃红 101 的两种单磺酰氯衍生物的混合物。

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

易制毒化学品（2类）
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
068K3799
058K3784
038K3776
028K1387
117K3780

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Jorge O Escobedo et al.
Natural product communications, 7(3), 317-320 (2012-05-02)
Understanding cellular mechanisms of ototoxic and nephrotoxic drug uptake, intracellular distribution, and molecular trafficking across cellular barrier systems aids the study of potential uptake blockers that preserve sensory and renal function during critical life-saving therapy. Herein we report the design
Sara Seabrooke et al.
The Journal of experimental biology, 215(Pt 17), 2945-2949 (2012-08-10)
We describe a method for calculating rates of fluorochrome transport from unstirred layer (USL) concentration gradients measured using confocal microscopy. Isolated Malpighian tubules or guts of Drosophila melanogaster were secured to depression slides and bathed in saline containing a fluorescent
Keiji Numata et al.
Biomacromolecules, 13(5), 1383-1389 (2012-04-05)
We developed a facile and quick ethanol-based method for preparing silk nanoparticles and then fabricated a biodegradable and biocompatible dual-drug release system based on silk nanoparticles and the molecular networks of silk hydrogels. Model drugs incorporated in the silk nanoparticles
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo.
Nimmerjahn A
Nature Materials, 1(1), 31-37 (2004)
Phillip M Uribe et al.
PloS one, 8(2), e55359-e55359 (2013-02-06)
Inner ear sensory hair cells die following exposure to aminoglycoside antibiotics or chemotherapeutics like cisplatin, leading to permanent auditory and/or balance deficits in humans. Zebrafish (Danio rerio) are used to study drug-induced sensory hair cell death since their hair cells
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