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Merck
CN

S4019

碳酸氢钠

Hybri-Max, powder, suitable for hybridoma, ≥99.5%

别名:

碳酸氢钠, 小苏打

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线性分子式:
NaHCO3
化学文摘社编号:
分子量:
84.01
UNSPSC Code:
12161702
NACRES:
NA.75
PubChem Substance ID:
EC Number:
205-633-8
Beilstein/REAXYS Number:
4153970
MDL number:
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InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

SMILES string

[Na+].OC([O-])=O

grade

Hybri-Max

assay

≥99.5%

form

powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

pH

8.3 (0.1 molfreshly prepared)

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

solubility

water: soluble 100 mg/mL

density

2.16 g/mL at 25 °C (lit.)

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Application

碳酸氢钠已作为一种补充剂:
  • 在极限必需培养基(MEM)/冲洗培养基中进行胚胎分离
  • 在TCM 199培养基中收集卵母细胞复合物(COC)并进行体外成熟(IVM)
  • 在IVM培养基中进行COC体外成熟

Biochem/physiol Actions

碳酸氢纳在自然状态下以纳石矿的形式存在。它可用于制备许多钠盐以及二氧化碳源。碳酸氢钠可用于制造灭火器和清洁剂。碳酸氢盐在体内pH调节中起着重要作用。碳酸氢钠在生物化学、分子生物学和色谱学中可用作缓冲剂。该Hybri-Max产物用于杂交瘤和细胞研究研究(2.2 mg/ml)。

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

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The effect of estrous ewe serum and heparin on in vitro fertilization and subsequent embryonic development in sheep
Li F, et al.
Small Ruminant Research, 63(3), 226-232 (2006)
The effects of L-ergothioneine and L-ascorbic acid on the in vitro maturation (IVM) and embryonic development (IVC) of sheep oocytes
Development, 1, 5-14 (2010)
Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This

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