Anti-Sirt6 (C-terminal) 兔抗

Sirtuin 6 (Sirt6) is a nuclear, chromatin-associated protein. Sirt6 is a member of Sir2 gene family. It is broadly expressed with the highest levels in muscle, brain and heart.

synthetic peptide corresponding to amino acids 330-348 of human Sirt6.

Anti-Sirt6 (C-terminal) antibody has been used in

• immunoblotting
• immunofluorescence
• western blotting
• immunohistochemistry

Sirtuin 6 (Sirt6) plays a key role in DNA repair and maintenance of genomic stability in cells. Sirt6 is enzymatically inactive as a NAD⁺ -dependent protein deacetylase but displays auto-ADP-ribosyltransferase activity. Loss of Sirt6 leads to the development of an acute degenerative aging-like phenotype.

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

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