Merck
CN

S4701

Sigma-Aldrich

Suplatast tosylate

≥98% (HPLC)

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别名:
(+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate, IPD-1151T, ST
经验公式(希尔记法):
C16H26SNO4 · C7H7SO3
CAS号:
分子量:
499.64
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

检测方案

≥98% (HPLC)

形式

powder

颜色

white to off-white

溶解性

DMSO: >20 mg/mL

储存温度

room temp

SMILES string

Cc1ccc(cc1)S([O-])(=O)=O.CCOCC(O)COc2ccc(NC(=O)CC[S+](C)C)cc2

InChI

1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)

InChI key

RYVJQEZJUFRANT-UHFFFAOYSA-N

应用

Suplatast tosylate may be used in immune-signaling studies.

生化/生理作用

Suplatast tosylate is a dimethylsulfonium compound downregulates the expression of histamine H1 receptor gene, suppresses the activity of histidine decarboxylase and regulates IL-4 mRNA. It inhibits the release of histamines and regulates the production of IgE.1,2 Suplatast tosylate is effective in the treatment of mild-to-moderate persistent asthma in children.3
Suplatast tosylate is an anti-allergy, cytokine modulator.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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