contains
sodium phosphate buffer as balance
Quality Segment
composition
Protein, ~25% Lowry
availability
not available in USA
impurities
Staphylococcal enterotoxin A (SEA), essentially free
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
General description
Staphylococcal Enterotoxin B (SEB) is a potent exotoxin produced by Staphylococcus aureus, classified as a superantigen due to its unique ability to activate T-cells non-specifically. This activation occurs through the cross-linking of T-cell receptors (TCRs) and major histocompatibility complex (MHC) class II molecules, leading to a massive release of cytokines and an exaggerated immune response. SEB is associated with food poisoning and toxic shock syndrome, making it a critical agent for studying the mechanisms of bacterial pathogenesis and immune dysregulation.
In addition to its role in infectious disease research, SEB serves as a valuable tool for investigating autoimmune conditions and the development of immunotherapies. Its ability to induce T-cell activation and proliferation makes it an important reagent for exploring T-cell biology, including differentiation, memory formation, and the effects of various immunomodulators.
In addition to its role in infectious disease research, SEB serves as a valuable tool for investigating autoimmune conditions and the development of immunotherapies. Its ability to induce T-cell activation and proliferation makes it an important reagent for exploring T-cell biology, including differentiation, memory formation, and the effects of various immunomodulators.
Application
与 MHC II 类分子和 T 细胞受体(TCR)的特异性 Vβ 区结合的葡萄球菌肠毒素 B(SEB),可导致单核细胞/巨噬细胞和 T 淋巴细胞的激活,可用作超抗原和免疫系统激活剂。 SEB 可用作 SEB 检测系统开发中的参考材料。
Packaging
包装尺寸基于蛋白质含量。
signalword
Danger
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
