impurities
<1 ng/mg protein endotoxin, <5 % of normal lipoprotein
shipped in
dry ice
storage temp.
−20°C
biological source
bovine fetus
form
frozen liquid
concentration
≥14 mg protein/mL Biuret
Quality Level
General description
研究表明，使用脂蛋白缺乏血清条件下培养的人成纤维细胞中甾醇的产生减少。
Application
来自胎牛的脂蛋白缺乏血清已被用作培养基中的补充剂，用于培养中国仓鼠卵巢（CHO）衍生细胞、胸腺叶和人外周血单核细胞（PBMC）。
Preparation Note
无菌过滤， 0.2 μm
用 Dulbecco′s 磷酸盐缓冲盐水（pH 7.4-7.5）进行透析
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
法规信息
监管及禁止进口产品
此项目有
Brian T Emmer et al.
PLoS genetics, 17(1), e1009285-e1009285 (2021-01-30)
Hypercholesterolemia is a causal and modifiable risk factor for atherosclerotic cardiovascular disease. A critical pathway regulating cholesterol homeostasis involves the receptor-mediated endocytosis of low-density lipoproteins into hepatocytes, mediated by the LDL receptor. We applied genome-scale CRISPR screening to query the
P M Giles et al.
Clinica chimica acta; international journal of clinical chemistry, 113(2), 183-191 (1981-06-18)
The biosynthesis and efflux of sterols from cells into the medium were investigated in skin fibroblasts from a control, a patient with obligate heterozygous familial hypercholesterolaemia and a patient with the homozygous condition. The behaviour of the cells was studied
Liliana M R Silva et al.
Frontiers in cellular and infection microbiology, 12, 809606-809606 (2022-03-01)
Apicomplexan parasites are considered as defective in cholesterol synthesis. Consequently, they need to scavenge cholesterol from the host cell by either enhancing the uptake of extracellular cholesterol sources or by upregulating host cellular de-novo biosynthesis. Given that Eimeria bovis macromeront
Ning Huangfu et al.
Frontiers in cell and developmental biology, 9, 687169-687169 (2021-07-23)
Atherosclerosis (AS), characterized by cholesterol overloaded-macrophages accumulation and plaque formation in blood vessels, is the major cause of cardiovascular disease. Transactive response DNA-binding protein∼43 kDa (TDP43) has recently been identified as an independent driver of neurodegenerative diseases through triggering inflammatory
Sterol regulatory element-binding protein (SREBP) cleavage regulates Golgi-to-endoplasmic reticulum recycling of SREBP cleavage-activating protein (SCAP)
Shao W and Espenshade PJ
The Journal of Biological Chemistry, 289(11), 7547-7557 (2014)
实验方案
Protect your investment with best practices for storing and thawing FBS and other sera. Sample FBS for validation in your cell culture protocol.
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