S5451
Sarpogrelate hydrochloride
≥98% (HPLC)
别名:
Anplag, Butanedioic acid 1-[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester hydrochloride, MCI 9042, Succinic acid mono-(1-dimethylaminomethyl-2-(2-[2-(3-methoxyphenyl)et hyl]phenoxy)ethyl) ester hydrochloride
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关于此项目
经验公式（希尔记法）:
C24H31NO6.HCl
化学文摘社编号:
分子量:
465.97
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
solubility
deionized water: ≥5 mg/mL
storage temp.
room temp
SMILES string
Cl.COc1cccc(CCc2ccccc2OCC(CN(C)C)OC(=O)CCC(O)=O)c1
InChI
1S/C24H31NO6.ClH/c1-25(2)16-21(31-24(28)14-13-23(26)27)17-30-22-10-5-4-8-19(22)12-11-18-7-6-9-20(15-18)29-3;/h4-10,15,21H,11-14,16-17H2,1-3H3,(H,26,27);1H
InChI key
POQBIDFFYCYHOB-UHFFFAOYSA-N
General description
Sarpogrelate hydrochloride binds to the serotonin receptor (5-hydroxytryptamine, 5-HT2A). Its binding to 5-HT2A receptor inhibits thrombus formation and reduces platelet aggregation. Sarpogrelate hydrochloride has been used as an anti-atherosclerotic agent. It improves the endothelial function and may be useful for treating peripheral arterial disease. Use of sarpogrelate hydrochloride as 5-HT2A antagonist reduces urinary albumin levels in diabetic nephropathy.
Biochem/physiol Actions
Sarapogrelate hydrochloride is a potent and selective 5-HT2A receptor antagonist.
Sarapogrelate hydrochloride is a potent and selective 5-HT2A receptor antagonist. It exhibits analgesic effects in numerous animal studies.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable