S5628
Ser-Tyr β-naphthylamide
powder
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关于此项目
经验公式（希尔记法）:
C22H23N3O4
化学文摘社编号:
分子量:
393.44
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
产品名称
Ser-Tyr β-naphthylamide, powder
InChI
1S/C22H23N3O4/c23-19(13-26)21(28)25-20(11-14-5-9-18(27)10-6-14)22(29)24-17-8-7-15-3-1-2-4-16(15)12-17/h1-10,12,19-20,26-27H,11,13,23H2,(H,24,29)(H,25,28)
SMILES string
NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)Nc2ccc3ccccc3c2
InChI key
MAQKGNBGUVFWNR-UHFFFAOYSA-N
assay
≥98% (TLC)
form
powder
color
off-white
solubility
ethanol: 50 mg/mL, clear, colorless to light yellow
storage temp.
−20°C
Quality Level
General description
Substrate for cathepsin C
Properties of dipeptidyl arylamidase I of the pituitary. Chloride and sulfhydryl activation of seryltyrosyl-beta-naphthylamide hydrolysis.
J K McDonald et al.
The Journal of biological chemistry, 241(7), 1494-1501 (1966-04-10)
M J McGuire et al.
Archives of biochemistry and biophysics, 295(2), 280-288 (1992-06-01)
The lysosomal hydrolase, dipeptidyl peptidase I (DPPI), was purified from human spleen and its enzymatic activity characterized. The enzyme was purified to apparent homogeneity by a combination of differential pH solubility, heat-treatment, affinity chromatography on concanavalin A-agarose and p-hydroxymercuribenzoate-agarose, and
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