S6626
毒毛旋花子苷元
cardiotonic steroid
别名:
3β,5,14-三羟基-19-氧-5β,20(22)-强心苷, ;毒毛旋花苷配基, K-毒毛旋花子甙元, 毒毛旋花子甙元, 毒毛旋花子苷K, 毒毛旋花子苷元, 毒毛旋花甙元, 羊角拗定, 羊角拗甾醇
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C23H32O6
化学文摘社编号:
分子量:
404.50
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-626-6
MDL number:
产品名称
毒毛旋花子苷元,
InChI
1S/C23H32O6/c1-20-6-3-17-18(4-8-22(27)11-15(25)2-7-21(17,22)13-24)23(20,28)9-5-16(20)14-10-19(26)29-12-14/h10,13,15-18,25,27-28H,2-9,11-12H2,1H3
InChI key
ODJLBQGVINUMMR-UHFFFAOYSA-N
SMILES string
C[C@@]12[C@@](CC[C@@H]2C(CO3)=CC3=O)(O)[C@]4([H])CC[C@]5(O)C[C@@H](O)CC[C@]5(C([H])=O)[C@@]4([H])CC1
storage temp.
−20°C
Quality Level
正在寻找类似产品? 访问 产品对比指南
相关类别
Application
毒毛旋花子甙元可用于合成乙酰毒毛旋花子甙元，已研究其对狗隐静脉神经递质释放的影响。3
Biochem/physiol Actions
毒毛旋花子甙元(Strophanthidin)是一种强心苷，可提高心肌细胞中的Na+/K+-ATP酶活性。1在兔肾皮质切片中，它可降低钾含量，提高钠含量。2
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Beni Shpak et al.
European journal of pharmacology, 553(1-3), 196-204 (2006-11-03)
Previous studies demonstrated that the purified endogenous inhibitor (NCX(IF)) of the cardiac Na(+)/Ca(2+) exchanger (NCX1) has the capacity to modulate cardiac muscle contractility. Here, we tested the effects of purified NCX(IF) on arrhythmias induced by ouabain in the atria and
Mark R Fowler et al.
Cardiovascular research, 62(3), 529-537 (2004-05-26)
Recent work has suggested that Na(+)/Ca(2+) exchange (NCX) and L-type Ca(2+) current (I(Ca)) are located predominantly in the t-tubules of cardiac ventricular myocytes, which therefore represent a microdomain for the regulation of intracellular Na(+) (Na(i)) and Ca(2+) (Ca(i)). The aim
Sara Arganda et al.
Nature neuroscience, 10(11), 1467-1473 (2007-10-02)
Pump activity is a homeostatic mechanism that maintains ionic gradients. Here we examined whether the slow reduction in excitability induced by sodium-pump activity that has been seen in many neuronal types is also involved in neuronal coding. We took intracellular
Dirk von Lewinski et al.
European journal of heart failure, 9(11), 1086-1094 (2007-10-25)
Cardiac glycosides are characterized by a narrow therapeutic range with Ca2+-overload and arrhythmias occurring at higher concentrations. Data on cardiac glycosides in isolated failing human myocardium are scarce and the frequency-dependent actions and toxicity of Strophanthidin have not yet been
Dhanasekhar Reddy et al.
Frontiers in oncology, 9, 1469-1469 (2020-02-06)
Lung cancer is the most prevalent in cancer-related deaths, while breast carcinoma is the second most dominant cancer in women, accounting for the most number of deaths worldwide. Cancers are heterogeneous diseases that consist of several subtypes based on the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持