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Merck
CN

S6760

Span® 80

nonionic surfactant

别名:

去水山梨糖醇单油酸酯

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关于此项目

化学文摘社编号:
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161900
EC Number:
215-665-4
MDL number:
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产品名称

Span® 80, nonionic surfactant

InChI key

NWGKJDSIEKMTRX-AAZCQSIUSA-N

InChI

1S/C24H44O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27)29-19-21(26)24-23(28)20(25)18-30-24/h9-10,20-21,23-26,28H,2-8,11-19H2,1H3/b10-9-/t20-,21+,23+,24+/m0/s1

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O

mol wt

428.62 g/mol

concentration

≥60% (GC)

HLB

4.3

application(s)

microbiology

Quality Level

Application

Span® 80已在一项研究中用于评估作为舍曲林转移体传递体经皮给药系统的作用。 它被应用于一项通过应用人工神经网络(ANNs)研究影响纳米乳稳定性的主要因素。

General description

Span® 80是一种非离子表面活性剂。

Other Notes

脂肪酸组成:油酸(C18:1) ≤60%;主要平衡亚油酸(C18:2)、亚麻酸(C18:3)和棕榈酸(C16:0)。

Legal Information

Span is a registered trademark of Croda International PLC

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ankit Gupta et al.
Scientia pharmaceutica, 80(4), 1061-1080 (2012-12-25)
The aim of the present study was to investigate transfersomes as a transdermal delivery system for the poorly soluble drug, sertraline, in order to overcome the troubles associated with its oral delivery. Different transfersomal formulations were prepared with non-ionic surfactant
Jean-François Cotte et al.
International journal of pharmaceutics, 436(1-2), 233-239 (2012-06-21)
Mass spectrometry (MS) and high performance liquid chromatography coupled to mass spectrometry (HPLC-MS) techniques were developed to characterize two surfactants, cetheareth-12 and sorbitan oleate, used to manufacture AF03, an emulsified oil-in-water (O/W) adjuvant. MS was first used to characterize the
Hoang Hirschberg et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(1-2), 1-7 (2012-02-15)
In the search for an optimal approach for the transcutaneous immunization (TCI) of hepatitis B surface antigen (HBsAg), two vesicle formulations, L595 vesicles (composed of sucrose-laurate ester and octaoxyethylene-laurate ester) and sPC vesicles (composed of soybean-phosphatidylcholine and Span-80) were prepared
Daniela S Bernardi et al.
Journal of nanobiotechnology, 9, 44-44 (2011-09-29)
Nanoemulsions have practical application in a multitude of commercial areas, such as the chemical, pharmaceutical and cosmetic industries. Cosmetic industries use rice bran oil in sunscreen formulations, anti ageing products and in treatments for skin diseases. The aim of this
Praneeth Reddy Devulapally et al.
Genome medicine, 10(1), 34-34 (2018-04-29)
Existing methods for paired antibody heavy- and light-chain repertoire sequencing rely on specialized equipment and are limited by their commercial availability and high costs. Here, we report a novel simple and cost-effective emulsion-based single-cell paired antibody repertoire sequencing method that

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