S6826
司替戊醇
≥98% (HPLC), Anti-convulsant reagent, powder
别名:
4,4-dimethyl-1-[3,4(methylenedioxy)-phenyl]-1-penten-3-ol, Diacomit
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关于此项目
经验公式（希尔记法）:
C14H18O3
化学文摘社编号:
分子量:
234.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
256-480-9
MDL number:
产品名称
司替戊醇, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: ≥20 mg/mL
storage temp.
−20°C
SMILES string
CC(C)(C)C(O)\C=C\c1ccc2OCOc2c1
InChI
1S/C14H18O3/c1-14(2,3)13(15)7-5-10-4-6-11-12(8-10)17-9-16-11/h4-8,13,15H,9H2,1-3H3/b7-5+
InChI key
IBLNKMRFIPWSOY-FNORWQNLSA-N
Application
Stiripentol has been used in pharmacokinetic analysis and as a reference standard in fluorescence spectra analysis.
Stiripentol may be used in GABAA receptor-mediated cell signaling studies.
Biochem/physiol Actions
Anti-convulsant drug
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Yushi Inoue et al.
Epilepsia, 50(11), 2362-2368 (2009-06-26)
To survey the treatment situation of Dravet syndrome in Japan and to compare this result with effectiveness of stiripentol (STP) add-on therapy in an open-label multicenter study. Medical records of patients with Dravet syndrome who visited the study institutions during
Atsushi Fujiwara et al.
Journal of anesthesia, 34(3), 373-381 (2020-03-20)
Antiepileptic drugs are used not only for the treatment of epilepsy but also for that of neuropathic pain. However, their action mechanisms have not always been well explained. Stiripentol, an effective antiepileptic drug indicated as a therapeutic for Dravet syndrome
Rima Nabbout et al.
Epilepsia, 52(7), e54-e57 (2011-05-17)
We aimed to test the efficacy of ketogenic diet (KD) in patients with Dravet syndrome (DS) not satisfactorily controlled by antiepileptic drugs (AEDs). We included prospectively 15 DS patients aged >3 years with partial response to AEDs including stiripentol. All
Paolo Prunetti et al.
Current opinion in neurology, 24(2), 159-164 (2011-02-09)
There is a need for newer anti-epileptic drugs (AEDs) with improved efficacy and tolerability. This article reviews AEDs introduced since 2007 and investigational compounds in clinical development. Two recently introduced AEDs, stiripentol and rufinamide, have been licensed exclusively for orphan
Catherine Chiron
Developmental medicine and child neurology, 53 Suppl 2, 16-18 (2011-04-29)
Dravet syndrome is a highly pharmaco-resistant form of epilepsy. Valproate and benzodiazepines are the first-line treatment but are usually insufficient therapeutic options. Lamotrigine, carbamazepine and high doses of intravenous phenobarbital can aggravate seizures and should be avoided. Topiramate, levetiracetam, bromide
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S6826-5MG | 04061832559612 |
| S6826-25MG | 04061836959616 |
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