S6879
D-鞘氨醇
from bovine brain, ~99% (TLC)
别名:
4-鞘氨醇, 反式-D-赤-2-氨基-4-十八烯-1，3-二醇, （2S，3R，4E）-2-氨基-4-十八烯-1，3-二醇
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关于此项目
经验公式（希尔记法）:
C18H37NO2
化学文摘社编号:
分子量:
299.49
EC Number:
204-651-3
UNSPSC Code:
12352211
PubChem Substance ID:
Beilstein/REAXYS Number:
1727294
MDL number:
InChI key
WWUZIQQURGPMPG-KRWOKUGFSA-N
InChI
1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
SMILES string
OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
biological source
bovine brain
assay
~99% (TLC)
storage temp.
−20°C
Gene Information
human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584)
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Application
D-Sphingosine from bovine brain was tested for effects on distribution of clathrin/AP-2 in cultured fibroblasts.8 It was used to prepare vesicles and study the interactions of DNA with bilayers of cationic liposomes.9
Biochem/physiol Actions
细胞膜的一种组成部分。神经酰胺的前体。蛋白激酶 C 的选择性抑制剂，但不抑制蛋白激酶 A 或肌球蛋白轻链激酶。钙调蛋白依赖性酶的抑制剂。
Preparation Note
Prepared from sphingomyelin.
Analysis Note
May contain small amounts of structural analogues.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
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