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S7129

O-琥珀酰-L-高丝氨酸

Name: O-琥珀酰-<SC>L</SC>-高丝氨酸
Brand: SIGMA

≥98.0% (TLC), suitable for ligand binding assays

别名:

L-Homoserine 4-(hydrogen butanedioate)

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关于此项目

经验公式（希尔记法）:

C₈H₁₃NO₆

化学文摘社编号:

1492-23-5

分子量:

219.19

UNSPSC Code:

12352209

PubChem Substance ID:

24899732

NACRES:

NA.26

MDL number:

MFCD00055782

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产品名称

O-琥珀酰-L-高丝氨酸,

assay

≥98.0% (TLC)

Quality Level

100

form

powder

technique(s)

ligand binding assay: suitable

color

white

storage temp.

−20°C

SMILES string

N[C@@H](CCOC(=O)CCC(O)=O)C(O)=O

InChI

1S/C8H13NO6/c9-5(8(13)14)3-4-15-7(12)2-1-6(10)11/h5H,1-4,9H2,(H,10,11)(H,13,14)/t5-/m0/s1

InChI key

GNISQJGXJIDKDJ-YFKPBYRVSA-N

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Enzymatic characterization and inhibitor discovery of a new cystathionine {gamma}-synthase from Helicobacter pylori.

Yunhua Kong et al.

Journal of biochemistry, 143(1), 59-68 (2007-11-06)

Cystathionine gamma-synthase (CGS) catalyses the first step of the transsulfuration pathway that converts l-cysteine to l-homocysteine in bacteria, whereas this pathway is absent in human. In this report, we identified a new metB gene from Helicobacter pylori strain SS1, and

Cloning and characterization of two Lactobacillus casei genes encoding a cystathionine lyase.

Stefan Irmler et al.

Applied and environmental microbiology, 74(1), 99-106 (2007-11-13)

Volatile sulfur compounds are key flavor compounds in several cheese types. To better understand the metabolism of sulfur-containing amino acids, which certainly plays a key role in the release of volatile sulfur compounds, we searched the genome database of Lactobacillus

Direct homocysteine biosynthesis from O-succinylhomoserine in Escherichia coli: an alternate pathway that bypasses cystathionine.

M Simon et al.

Journal of bacteriology, 153(1), 558-561 (1983-01-01)

Mutations were found which enable Escherichia coli K-12 to form homocysteine in the absence of cystathionase. The formation of homocysteine in the mutant strains required cystathionine gamma-synthetase, the metB gene product, but bypassed the normal intermediate cystathionine. It is concluded

A direct sulfhydrylation pathway is used for methionine biosynthesis in Pseudomonas aeruginosa.

M Foglino et al.

Microbiology (Reading, England), 141 ( Pt 2), 431-439 (1995-02-01)

The relationship between genes and enzymes in the methionine biosynthetic pathway has been studied in Pseudomonas aeruginosa. The first step is catalysed by an O-succinylhomoserine synthase, the product of the metA gene mapped at 20 min on the chromosome. The

Escherichia coli cystathionine gamma-synthase does not obey ping-pong kinetics. Novel continuous assays for the elimination and substitution reactions.

Susan M Aitken et al.

Biochemistry, 42(38), 11297-11306 (2003-09-25)

Cystathionine gamma-synthase (CGS) is a pyridoxal phosphate-dependent enzyme that catalyzes a gamma-replacement reaction, in which the succinyl group of an O-succinyl-L-homoserine (L-OSHS) is displaced by the thiol of L-cysteine to form L-cystathionine, in the first step of the bacterial transsulfuration

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全球贸易项目编号

货号	GTIN
S7129-100MG	04061832726847
S7129-25MG	04061832726854

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