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S7323

14-3-3 Sigma histidine-tagged human

Name: 14-3-3 Sigma histidine-tagged human
Brand: SIGMA

recombinant, expressed in E. coli, C-terminal, ≥90% (SDS-PAGE), buffered aqueous glycerol solution

别名:

14-3-3σ, Epitheliial cell marker protein 1, HME1, Makorin, ring finger protein 3, Mkrn3, Mmel, SFN, Stratifin, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, sigma polypeptide, YWHAS

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关于此项目

NACRES:

NA.32

UNSPSC Code:

12352202

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属性

recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

form

buffered aqueous glycerol solution

mol wt

~30 kDa (14-3-3 proteins)

UniProt accession no.

P31947

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... SFN(2810)

说明

Biochem/physiol Actions

14-3-3 proteins are involved in a multitude of biological processes and play a regulatory role in processes such as apoptotic cell death, mitogenic signal transduction, and cell cycle control. 14-3-3σ proteins play a critical role in signal transduction pathways and cell cycle regulation. 14-3-3σ is the only 14-3-3 isoform induced by the tumor suppressor protein p53, in response to γ-irradiation and other DNA-damaging agents. 14-3-3σ is a p53-regulated inhibitor of G2/M progression and acts as a tumor suppressor gene that is inactivated by methylation of its 5′ CpG islands in epithelial tumor cells.

Physical form

Supplied as a 0.2 μm filtered solution in 50 mM Tris-HCl, pH 7.6, 1 mM EDTA, 1 mM DTT, and 20% glycerol (w/v).

wgk

WGK 1

存储类别

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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全球贸易项目编号

货号	GTIN
S7323-100UG	04061838033222