S7448
STF-62247
≥98% (HPLC), solid
别名:
N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine
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关于此项目
经验公式（希尔记法）:
C15H13N3S
化学文摘社编号:
分子量:
267.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality Segment
assay
≥98% (HPLC)
form
solid
solubility
DMSO: soluble 26 mg/mL, H2O: insoluble
storage temp.
room temp
SMILES string
Cc1cccc(Nc2nc(cs2)-c3ccncc3)c1
InChI
1S/C15H13N3S/c1-11-3-2-4-13(9-11)17-15-18-14(10-19-15)12-5-7-16-8-6-12/h2-10H,1H3,(H,17,18)
InChI key
KATNUHQNJGNLPW-UHFFFAOYSA-N
Application
STF-62247 may be used as positive control in autophagy inducing cell signaling studies.
Biochem/physiol Actions
STF-62247 is a selective inducer of autophagy in VHL-deficient renal cell carcinoma cells.
STF-62247 induces the formation of large vacuoles in the von Hippel-Lindau deficient renal carcinoma cells, a characteristic of autophagy.1
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
存储类别
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges