S8439
硬脂酰乙醇酰胺
≥98%, crystalline
别名:
N-硬脂酰乙醇胺, NSE
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关于此项目
经验公式（希尔记法）:
C20H41NO2
化学文摘社编号:
分子量:
327.55
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
203-883-2
MDL number:
Form:
crystalline
Assay:
≥98%
产品名称
硬脂酰乙醇酰胺, ≥98%, crystalline
InChI
1S/C20H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h22H,2-19H2,1H3,(H,21,23)
InChI key
OTGQIQQTPXJQRG-UHFFFAOYSA-N
SMILES string
CCCCCCCCCCCCCCCCCC(=O)NCCO
assay
≥98%
form
crystalline
storage temp.
−20°C
Quality Level
Gene Information
rat ... Cnr1(25248)
Application
硬脂酰乙醇酰胺（NSE）已用作使用薄层色谱法定量内部合成NSE的标准品。
Biochem/physiol Actions
PLD水解细胞膜磷脂产生的最丰富的脂肪酸乙醇酰胺。
General description
硬脂酰乙醇酰胺，也称为N-硬脂酰乙醇胺（NSE），普遍存在于所有哺乳动物中。合成时以三种亚型存在。它具有调节免疫和炎症反应的治疗潜力。它还具有抗氧化和膜保护功能。NSE分子以尾到尾的方式堆积在脂质双层中。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
n-stearoylethanolamine protects the brain and improves memory of mice treated with lipopolysaccharide or immunized with the extracellular domain of alpha7 nicotinic acetylcholine receptor
Lykhmus O, et al.
International Immunopharmacology, 52, 290-296 (2017)
Effects of N-stearoylethanolamine on anxiety-like behavioral reactions of rats after chronic alcoholization
Bondarenko OV, et al.
Biologija, 60(1) (2014)
Nazdar Ghafouri et al.
PloS one, 6(11), e27257-e27257 (2011-11-30)
N-acylethanolamines (NAEs) are endogenous compounds that regulate inflammation and pain. These include the cannabinoid ligand anandamide (AEA) and the peroxisome proliferator-activated receptor-α ligand palmitoylethanolamide (PEA). Little is known as to the levels of NAEs in pain states in human, particularly
Structure and phase behavior of O-stearoylethanolamine: A combined calorimetric, spectroscopic and X-ray diffraction study
Tarafdar PK and Swamy MJ
Biochimica et Biophysica Acta - Biomembranes, 1798(5), 872-881 (2010)
Salvatore Terrazzino et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 18(13), 1580-1582 (2004-08-04)
Given the recent demonstration that oleoylethanolamide (OEA), a cannabinoid receptor-inactive N-acylethanolamine, decreases food intake by activating the nuclear receptor PPARalpha (peroxisome proliferator-activated receptor alpha) in the periphery, we here evaluated the effects of both saturated and unsaturated C18 N-acylethanolamides (C18:0;
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