S8502
(−)-Scopolamine methyl bromide
≥98% (HPLC), mAChRs antagonist, powder
别名:
Hyoscine methyl bromide, Methscopolamine bromide
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关于此项目
经验公式（希尔记法）:
C18H24NO4 · Br
化学文摘社编号:
分子量:
398.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
205-844-5
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
产品名称
(−)-Scopolamine methyl bromide, ≥98% (HPLC), powder
Quality Segment
assay
≥98% (HPLC)
form
powder
optical activity
[α]25/D −25°, c = 5 in H2O(lit.)
color
white
solubility
H2O: 50 mg/mL
SMILES string
[Br-].[H][C@]12C[C@@H](C[C@]([H])([C@@]3([H])O[C@@]13[H])[N+]2(C)C)OC(=O)[C@H](CO)c4ccccc4
InChI
1S/C18H24NO4.BrH/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11;/h3-7,12-17,20H,8-10H2,1-2H3;1H/q+1;/p-1/t12-,13-,14-,15+,16-,17+;/m1./s1
InChI key
CXYRUNPLKGGUJF-RAFJPFSSSA-M
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
Application
(−)-Scopolamine methyl bromide was administered to rats to inhibit the peripheral cholinergic effects induced by pilocarpine.10,11
Biochem/physiol Actions
Competitive muscarinic acetylcholine receptor antagonist.
Scopolamine is an anti-muscarinic and cholinolytic alkaloid that inhibits parasympathetic-cholinergic system.7 The central effects include hallucinations, disorientation, restlessness and euphoria.8 Scopolamine disturb the stimulus detection performance in rats by interfering with the reticular cholinergic pathways.9
Disclaimer
Shelf-life of the powder is at least five years when stored at room temperature.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Acute 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves