S8754
茄尼醇 来源于烟草
≥90% (HPLC)
别名:
Betulanonaprenol, Nonaisoprenol
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关于此项目
经验公式（希尔记法）:
C45H74O
化学文摘社编号:
分子量:
631.07
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352212
MDL number:
InChI key
AFPLNGZPBSKHHQ-MEGGAXOGSA-N
SMILES string
C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CO
InChI
1S/C45H74O/c1-37(2)19-11-20-38(3)21-12-22-39(4)23-13-24-40(5)25-14-26-41(6)27-15-28-42(7)29-16-30-43(8)31-17-32-44(9)33-18-34-45(10)35-36-46/h19,21,23,25,27,29,31,33,35,46H,11-18,20,22,24,26,28,30,32,34,36H2,1-10H3/b38-21+,39-23+,40-25+,41-27+,42-29+,43-31+,44-33+,45-35+
assay
≥90% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
Quality Level
General description
茄尼醇(Solanesol)主要从烟草(Nicotiana tabacum)中提取而来。它是一种脂肪萜类、聚异戊二烯醇。茄尼醇还分布于其他茄科植物中，如番茄 、土豆 、茄子、甜椒(bell pepper)。这种C45异戊二烯醇是烟叶中蕴含最丰富的脂质。
Application
烟草茄尼醇可作为参考标准品，通过反相高效液相色谱(RP-HPLC)定量分析不同烟叶样品中的茄尼醇。它可增强人造脂质体稳定性，用于检测渗透压应激下泛醌-8(Q8)介导的大肠杆菌膜的机械稳定性。
Biochem/physiol Actions
茄尼醇具有抗氧化、抗炎、神经保护和抗菌作用。还可结合硫代水杨酸(TS)和透明质酸(HA)作为药物载体，发挥抗癌作用。茄尼醇是烟气中的致瘤性多核芳香烃的重要前体。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Ning Yan et al.
Biomolecules, 9(8) (2019-08-07)
Solanesol, an aliphatic terpene alcohol composed of nine isoprene units, is mainly found in solanaceous plants. Particularly, tobacco (Nicotiana tabacum), belonging to the Solanaceae family, is the richest plant source of solanesol, and its leaves have been regarded as the
Severson, R.F., et al.
Journal of Chromatographic Science, 139, 269-269 (1977)
Lequan Qiu et al.
Journal of microbiology and biotechnology, 21(5), 494-502 (2011-05-28)
Coenzyme Q10 (CoQ10) is a widely used supplement in heart diseases treatment or antioxidative dietary. The microbial production of CoQ10 was enhanced by addition of solanesol and novel precursors recovered from waste tobacco. The novel precursors were separated by silica
Peter A Machado et al.
Bioresource technology, 101(3), 1091-1096 (2009-09-24)
Solanesol in the waste streams of a bioprocess designed for alternative applications of low-alkaloid tobacco was recovered using three different extraction methods. Compared to the conventional heat-reflux extraction (HRE) and ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE) using 1:3 hexane:ethanol (v/v)
R Nageswara Rao et al.
Journal of pharmaceutical and biomedical analysis, 46(2), 310-315 (2007-11-27)
A method of continuous counter current extraction in a large-scale production of solanesol from tobacco leaves was developed. The crude extract containing 15-20% solanesol was subjected to a series of steps, viz., saponification, solvent recrystallization and column chromatography. The pure
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