S8758
N-Succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin
protease substrate, ≥98%, powder
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关于此项目
经验公式（希尔记法）:
C29H32N4O8
化学文摘社编号:
分子量:
564.59
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
MDL number:
产品名称
N-Succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin, protease substrate
Quality Level
assay
≥98%
form
powder
solubility
50% acetic acid: 1 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(NC(=O)CCC(O)=O)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)Nc2ccc3C(C)=CC(=O)Oc3c2
InChI
1S/C29H32N4O8/c1-16-13-26(37)41-23-15-20(9-10-21(16)23)32-29(40)22(14-19-7-5-4-6-8-19)33-28(39)18(3)31-27(38)17(2)30-24(34)11-12-25(35)36/h4-10,13,15,17-18,22H,11-12,14H2,1-3H3,(H,30,34)(H,31,38)(H,32,40)(H,33,39)(H,35,36)
InChI key
HHPVJKZZYOXPLH-UHFFFAOYSA-N
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Naoto Watamura et al.
Molecular psychiatry (2021-11-06)
Alzheimer's disease (AD) is characterized by the deposition of amyloid β peptide (Aβ) in the brain. The neuropeptide somatostatin (SST) regulates Aβ catabolism by enhancing neprilysin (NEP)-catalyzed proteolytic degradation. However, the mechanism by which SST regulates NEP activity remains unclear.
Christiane Ott et al.
Redox biology, 46, 102106-102106 (2021-08-30)
Removal of moderately oxidized proteins is mainly carried out by the proteasome, while highly modified proteins are no longer degradable. However, in the case of proteins modified by nitration of tyrosine residues to 3-nitrotyrosine (NO2Y), the role of the proteasome
Maria J Xavier et al.
Animals : an open access journal from MDPI, 11(6) (2021-07-03)
The larval stage is highly prone to stress due to the ontogenetic and metabolic alterations occurring in fish. Curcumin inclusion in diets has been shown to improve growth by modulating oxidative status, immune response, and/or feed digestibility in several fish
Fadi Rofo et al.
Theranostics, 11(2), 789-804 (2021-01-05)
Background: Aggregation of the amyloid-beta (Aβ) peptide is one of the main neuropathological events in Alzheimer's disease (AD). Neprilysin is the major enzyme degrading Aβ, with its activity enhanced by the neuropeptide somatostatin (SST). SST levels are decreased in the
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S8758-5MG | 04061832910222 |
| S8758-25MG | 04061832910215 |
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