S8817
SB 218795
>98% (HPLC)
别名:
(−)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide
登录并加购，请在购物车里查看协议价、货期和发货地。
选择规格
变更视图
关于此项目
经验公式（希尔记法）:
C25H20N2O3
分子量:
396.44
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Quality Segment
assay
>98% (HPLC)
form
solid
color
white
solubility
DMSO: soluble 40 mg/mL, H2O: insoluble
storage temp.
2-8°C
SMILES string
COC(=O)[C@H](NC(=O)c1cc(nc2ccccc12)-c3ccccc3)c4ccccc4
Gene Information
human ... TACR2(6865), TACR3(6870)
Application
The pharmacodynamics profile of SB 218795 enables its use as a tool to study physiological and pathophysiological roles of NK-3 receptor in CNS-modulated behaviors.
Biochem/physiol Actions
Non-peptide NK3 tachykinin receptor antagonist.
SB 218795 is a 2-phenyl-4-quinolinecarboxamides and a selective, reversible and competitive antagonist of human NK-3 receptor that effectively crosses the blood-brain barrier. It inhibits the NK-3 receptor-induced miosis or pupil constriction in conscious rabbits.1,2
Legal Information
Sold for research purposes under agreement from GlaxoSmithKline
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Gloves, type N95 (US)