S9311
SIB 1893
>99%, solid
别名:
[E]-2-Methyl-6-[2-phenylethenyl]pyridine
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关于此项目
经验公式（希尔记法）:
C14H13N
化学文摘社编号:
分子量:
195.26
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
>99%
Form:
solid
Quality Segment
assay
>99%
form
solid
solubility
DMSO: 18 mg/mL
storage temp.
2-8°C
SMILES string
Cc1cccc(\C=C\c2ccccc2)n1
InChI
1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
InChI key
SISOFUCTXZKSOQ-ZHACJKMWSA-N
Gene Information
human ... GRM1(2911), GRM5(2915)
Application
SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies.
Biochem/physiol Actions
SIB 1893 non-competitively inhibits glutamate-induced increase in Ca2+ at human metabotropic glutamate receptor 1 (hmGluR1).1 It also acts as a positive allosteric modulator of hmGluR4.2
Selective and noncompetitive mGlu5 metabotropic glutamate receptor antagonist.
Features and Benefits
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示词
Warning
危险代码
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
dust mask type N95 (US), Eyeshields, Gloves