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About This Item
经验公式（希尔记法）:
C14H13N
CAS Number:
分子量:
195.26
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
>99%
表单
solid
溶解性
DMSO: 18 mg/mL
储存温度
2-8°C
SMILES字符串
Cc1cccc(\C=C\c2ccccc2)n1
InChI
1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
InChI key
SISOFUCTXZKSOQ-ZHACJKMWSA-N
基因信息
human ... GRM1(2911), GRM5(2915)
应用
SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies.
生化/生理作用
SIB 1893 non-competitively inhibits glutamate-induced increase in Ca2+ at human metabotropic glutamate receptor 1 (hmGluR1).1 It also acts as a positive allosteric modulator of hmGluR4.2
Selective and noncompetitive mGlu5 metabotropic glutamate receptor antagonist.
特点和优势
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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