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Merck
CN

S9692

SU 6656

≥98% (HPLC)

别名:

2,3-二氢-N,N-二甲基-2-氧代-3-[(4,5,6,7-四氢-1H-吲哚-2-基)亚甲基]-1H-吲哚-5-磺酰胺

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关于此项目

经验公式(希尔记法):
C19H21N3O3S
化学文摘社编号:
分子量:
371.45
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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产品名称

SU 6656, ≥98% (HPLC)

InChI

1S/C19H21N3O3S/c1-22(2)26(24,25)14-7-8-18-15(11-14)16(19(23)21-18)10-13-9-12-5-3-4-6-17(12)20-13/h7-11,20H,3-6H2,1-2H3,(H,21,23)/b16-10-

SMILES string

CN(C)S(=O)(=O)c1ccc2NC(=O)C(=C/c3cc4CCCCc4[nH]3)\c2c1

InChI key

LOGJQOUIVKBFGH-YBEGLDIGSA-N

assay

≥98% (HPLC)

form

powder

storage condition

protect from light
under inert gas

color

orange-brown

solubility

DMSO: 12 mg/mL (orange solution)

storage temp.

−20°C

Quality Level

Gene Information

human ... SRC(6714)

Biochem/physiol Actions

SU 6656是一种选择性Src家族激酶抑制剂。
SU 6656是一种选择性Src家族激酶抑制剂。SU 6656可抑制CD34阳性选择的脐血细胞中的Src激酶。

Features and Benefits

这种化合物是激酶磷酸酶生物学研究的特色产品。点击此处发现更多特色激酶磷酸酶生物产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Roman Ginnan et al.
American journal of physiology. Cell physiology, 288(6), C1193-C1201 (2005-01-29)
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Regeneration following spinal root avulsion is broadly unsuccessful despite the regenerative capacity of other PNS-located nerves. By combining focal laser lesioning to model root avulsion in zebrafish, time-lapse imaging, and transgenesis, we identify that regenerating DRG neurons fail to recapitulate
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H C Chua et al.
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The sodium leak channel (NALCN) is essential for survival in mammals: NALCN mutations are life-threatening in humans and knockout is lethal in mice. However, the basic functional and pharmacological properties of NALCN have remained elusive. Here, we found that robust

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