S9701
舒巴坦酸
≥98% (HPLC), β-lactamases inhibitor, powder
别名:
(2S,5R)-3,3-二甲基-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸4,4-二氧化物, CP 45899, CP-45,899, 舒巴克坦, 青霉烷砜酸, 青霉酸1,1-二氧化物, 青霉酸二氧化物, 青霉酸砜
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关于此项目
经验公式（希尔记法）:
C8H11NO5S
化学文摘社编号:
分子量:
233.24
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
269-878-2
MDL number:
产品名称
舒巴坦酸,
InChI
1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1
InChI key
FKENQMMABCRJMK-RITPCOANSA-N
SMILES string
CC1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O
assay
98-102% (HPLC)
form
crystalline powder
color
white to off-white
solubility
H2O: 1%
storage temp.
2-8°C
Quality Level
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General description
舒巴坦是一种半合成青霉素砜，来源于6-氨基青霉烷酸。这种β-内酰胺化合物的特征为具有一个 β-内酰胺环。
Application
舒巴坦可用作β-内酰胺酶抑制剂测试中的β-内酰胺酶抑制剂。 它也可用于评估其对极端耐药的鲍曼不动杆菌的抗菌药效学作用。舒巴坦可用于细胞信号转导研究。
Biochem/physiol Actions
舒巴坦为 β-内酰胺酶的不可逆抑制剂，可使β-内酰胺如青霉素和头孢菌素失活。它也可对拟杆菌和革兰氏阴性菌的某些染色体介导酶起作用。它具有有限的抗菌活性。 但是，舒巴坦与其它潜在抗生素的联合使用对多重耐药型鲍曼不动杆菌感染有治疗作用。
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
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商品
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
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