Product Name
皂草素 来源于肥皂草 种子, lyophilized powder
生物来源
plant seeds (Saponaria officinalis)
质量水平
方案
10.00-30.00%
表单
lyophilized powder
组成
Protein, ~20% Lowry
技术
activity assay: suitable
储存温度
2-8°C
一般描述
来自皂角种子的皂草素具有一个 N-末端结构域，该结构域为 β-链和一个 C-末端结构域，即 α-螺旋形。由 253 个氨基酸组成，分子量为 28,621 Da。
应用
来自肥皂草种子的皂草素被用来研究它对轮状镰刀霉菌的抗真菌的活动。
生化/生理作用
来自皂角种子的皂草素是一种核糖体失活蛋白。用于制备免疫结合物。已被证明可诱导培养的人淋巴细胞形成微核，从而降低细胞活力，增强细胞凋亡。
包装
基于蛋白质含量的包装尺寸。
外形
含葡萄糖和磷酸钠缓冲盐的冻干粉
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
R Iglesias et al.
FEBS letters, 325(3), 291-294 (1993-07-05)
The type 1 ribosome-inactivating protein (RIP) saporin 5 isolated from seeds of Saponaria officinalis L. strongly inhibited translation carried out by Vicia sativa L. purified ribosomes. The toxin multidepurinated V. sativa rRNA, which upon treatment with acid aniline releases several
Elizabeth S Ingham et al.
The Journal of comparative neurology, 516(2), 125-140 (2009-07-04)
In mammals, non-image-forming visual functions, including circadian photoentrainment and the pupillary light reflex, are thought to be mediated by the combination of rods, cones, and the melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs). Although several genetic models have been developed
The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome.
Savino C
Febs Letters, 470(3), 239-243 (2000)
The amino acid sequence of a ribosome-inactivating protein from Saponaria officinalis seeds.
Maras B
Biochemistry International, 21(5), 831-838 (1990)
Analysis of the Sequence Preference of Saporin by Deep Sequencing.
Hauf, et al.
ACS chemical biology, 17, 2619-2630 (2023)
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