SAB1300686
Anti-CYP26A1 (center) antibody produced in rabbit
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
别名:
Anti-CYP26A1, Cytochrome P450, family 26, subfamily A, polypeptide 1 (Cytochrome P450, family 26, subfamily A, polypeptide 1, isoform CRA_b)
产品名称
Anti-CYP26A1 (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
saturated ammonium sulfate (SAS) precipitated
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CYP26A1(1592)
Biochem/physiol Actions
Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) is a retinoic acid (RA) degrading enzyme. It plays a vital role in RA metabolism. CYP26A1 has an essential role in the correct anteroposterior patterning and the generation of migratory cranial neural crest cells in the developing mammalian brain. Mutations in the gene is associated with the pathogenesis of optic nerve aplasia (ONA).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) is encoded by the gene mapped to human chromosome 10q23.33.
The previously assigned protein identifier Q5VXI0 has been merged into O43174. Full details can be found on the UniProt database.
The previously assigned protein identifier Q5VXI0 has been merged into O43174. Full details can be found on the UniProt database.
Immunogen
CYP26A1 (NP_000774, 123-157)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CYP26A1.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CYP26A1.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Nonsyndromic bilateral and unilateral optic nerve aplasia: first familial occurrence and potential implication of CYP26A1 and CYP26C1 genes.
Meire F
Molecular Vision, 17, 2072-2079 (2011)
Biochemical Basis for Dominant Inheritance, Variable Penetrance, and Maternal Effects in RBP4 Congenital Eye Disease.
Chou CM
Cell, 161, 634-646 (2015)
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