SAB1300711
Anti-MSH3 (center) antibody produced in rabbit
saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
别名:
Anti-DNA mismatch repair protein Msh3, Anti-DUP, Anti-Divergent upstream protein, Anti-MRP1, Mismatch repair protein 1
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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
indirect ELISA
western blot
western blot
Species reactivity:
human
Citations:
Technique(s):
indirect ELISA: 1:1000
western blot: 1:100-1:500
western blot: 1:100-1:500
Uniprot accession no.:
产品名称
Anti-MSH3 (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
saturated ammonium sulfate (SAS) precipitated
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MSH3(4437)
General description
MSH3 is a component of the post-replicative DNA mismatch repair system (MMR). THis protein heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, it forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
Immunogen
MSH3 (NP_002430, 464-497)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human MSH3.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human MSH3.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
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