产品名称
Anti-Rat Gpr81-r320 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
Quality Level
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, rat
technique(s)
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Northern analyses revealed GPR81 expression in the pituitary.
Immunogen
GPR81 (XP_001072594, 310-353)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the region of rat GPR81-R320.
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the region of rat GPR81-R320.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Sagor Chandra Roy et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 324(1), R20-R34 (2022-11-22)
Astrocytes store glycogen as energy and promote neurometabolic stability through supply of oxidizable l-lactate. Whether lactate regulates ventromedial hypothalamic nucleus (VMN) glucostatic function as a metabolic volume transmitter is unknown. Current research investigated whether G protein-coupled lactate receptor GPR81 controls
Haíssa de Castro Abrantes et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(23), 4422-4433 (2019-03-31)
The discovery of a G-protein-coupled receptor for lactate named hydroxycarboxylic acid receptor 1 (HCAR1) in neurons has pointed to additional nonmetabolic effects of lactate for regulating neuronal network activity. In this study, we characterized the intracellular pathways engaged by HCAR1
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