SAB1300971
Anti-PIK3R2 (Y467) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-PI3-kinase p85 subunit β, Anti-PIK3R2, Anti-Phosphatidylinositol 3-kinase regulatory subunit β, Anti-PtdIns-3-kinase p85-β
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: 1:1000, western blot: 1:100-1:500
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr467)
Gene Information
human ... PIK3R2(5296)
General description
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.
Immunogen
PIK3R2 (NP_005018, )
This antibody is generated from rabbits immunized with a peptide corresponding to amino acid residues surrounding Y467 of human PIK3R2.
This antibody is generated from rabbits immunized with a peptide corresponding to amino acid residues surrounding Y467 of human PIK3R2.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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存储类别
10 - Combustible liquids
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闪点 (F)
Not applicable
闪点 (°C)
Not applicable