SAB1302240
抗 小鼠 NLRP6（中心） 兔抗
IgG fraction of antiserum, buffered aqueous solution
别名:
LRR和PYD结构域包含蛋白6, NACHT, Nalp6, Nlrp6, Pypaf5
登录 查看组织和合同定价。
选择尺寸
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
mouse
Citations:
7
Technique(s):
western blot: 1:1000
Uniprot accession no.:
产品名称
抗 小鼠 NLRP6（中心） 兔抗, IgG fraction of antiserum, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
97402 Da
species reactivity
mouse
technique(s)
western blot: 1:1000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Nlrp6(101613)
Biochem/physiol Actions
NLR家族含pyri结构域蛋白6（NLRP6）在先天免疫中起作用。它也通过调节自噬和粘液分泌维持肠道稳态。已有研究证明NLRP6缺失可阻碍大鼠中白细胞介素-18（IL-18）的产生，并增进大鼠上皮诱导损伤的易感性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
NLR家族含pyri结构域蛋白6（NLRP6）可能是炎症小体的一部分。它属于NOD样受体家族，在肠上皮细胞中表达。
Physical form
纯化多克隆抗体以PBS为溶剂，含有0.09% (W/V) 叠氮化钠。该抗体通过蛋白A柱以及随后的肽亲和纯化进行纯化。
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
NLRP6 function in inflammatory monocytes reduces susceptibility to chemically induced intestinal injury.
Seregin SS
Mucosal Immunology (2017)
NLRP6 Protects Il10-/- Mice from Colitis by Limiting Colonization of Akkermansia muciniphila.
Seregin SS
Cellular Reprogramming (2017)
Pierre-Gregoire Coulon et al.
Frontiers in immunology, 10, 1631-1631 (2019-08-02)
The crosstalk between the host's inflammasome system and the invading virulent/less-virulent viruses determines the outcome of the ensuing inflammatory response. An appropriate activation of inflammasomes triggers antiviral inflammatory responses that clear the virus and heal the inflamed tissue. However, an
Junji Xing et al.
Cell reports, 35(12), 109205-109205 (2021-06-24)
RNA helicases play critical roles in various biological processes, including serving as viral RNA sensors in innate immunity. Here, we find that RNA helicase DEAH-box helicase 15 (DHX15) is essential for type I interferon (IFN-I, IFN-β), type III IFN (IFN-λ3)
Qifeng Deng et al.
Redox biology, 49, 102217-102217 (2021-12-24)
Maintaining host iron homeostasis is an essential component of nutritional immunity responsible for sequestrating iron from pathogens and controlling infection. Nucleotide-oligomerization domain-like receptors (NLRs) contribute to cytoplasmic sensing and antimicrobial response orchestration. However, it remains unknown whether and how NLRs
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持