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Merck
CN

SAB1303128

ANTI-IGHA1 (C-TERM) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

IGHA1, Ig alpha-1 chain C region

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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
FACS, IHC, WB
Citations:
6
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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

37655 Da

species reactivity

human

technique(s)

flow cytometry: 1:10-1:50, immunohistochemistry: 1:50-1:100, western blot: 1:250-1:500

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Quality Level

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Guoyuan Lu et al.
PloS one, 12(5), e0178352-e0178352 (2017-05-30)
IgA nephropathy (IgAN) is the most common primary glomerulonephritis characterized by human mesangial cells (HMC) proliferation and extracellular matrix expansion associated with immune deposits consisting of galactose-deficient IgA1. However, how IgA1 contributes to IgAN has yet to be completely elucidated.
Hossein Aazami et al.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 16, 30-30 (2020-05-01)
Chronic rhinosinusitis (CRS) describes an inflammatory condition affecting the sinonasal mucosa. As the immune system players such as immunoglobulins play prominent roles in the development of CRS, we aimed to investigate the expression of IgA subclasses and factors involved in
Lingyun Lai et al.
Discovery medicine, 28(151), 39-45 (2019-08-30)
It is widely accepted that a possible etiopathogenic factor associated with IgA nephropathy is the glycosylation of IgA1 molecule O-glycans. The present study aimed to determine if galactose-deficient IgA1 is related to glucose metabolism. IgA nephropathy was identified from the
Ying-Chih Chi et al.
Protein science : a publication of the Protein Society, 26(3), 600-610 (2016-12-29)
IgA1 proteases (IgA1P) from diverse pathogenic bacteria specifically cleave human immunoglobulin A1 (IgA1) at the hinge region, thereby thwarting protective host immune responses. Streptococcus pneumoniae (S. pneumoniae) IgA1P shares no sequence conservation with serine or cysteine types of IgA1Ps or
Erick S Sánchez-Salguero et al.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 72(2), 80-87 (2020-04-15)
Several studies have evaluated the effect of infectious diseases and vaccine protocols during pregnancy on maternal milk immunoglobulin (Ig) levels, to understand the protection conferred by lactation on newborns. Colostrum is the primary source of maternal IgA for the newborn.

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