SAB1306281
ANTI-SNAIL (N-TERM D24) 兔抗
IgG fraction of antiserum, buffered aqueous solution
别名:
Protein snail homolog 1, SNAH, SNAI1, Zinc finger protein SNAI1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human
Application:
immunohistochemistry
western blot
western blot
Technique(s):
immunohistochemistry: 1:10-1:50
western blot: 1:1000
western blot: 1:1000
Citations:
10
Uniprot accession no.:
产品名称
ANTI-SNAIL (N-TERM D24) 兔抗, IgG fraction of antiserum, buffered aqueous solution
biological source
rabbit
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
29083 Da
species reactivity
human
technique(s)
immunohistochemistry: 1:10-1:50
western blot: 1:1000
NCBI accession no.
UniProt accession no.
application(s)
research pathology
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SNAI1(6615)
Application
ANTI-SNAIL (N-TERM D24) antibody produced in rabbit has been used in Western Blotting.
Biochem/physiol Actions
Snail family transcriptional repressor 1 (SNAIL) acts as a repressor of genes associated with the epithelial phenotype like E-cadherin and increases the expression of genes linked with the mesenchymal phenotype. It has a role in epithelial-mesenchymal transition. The protein aids in G1 transition (early to late) in the cell cycle. SNAIL also modulates cell-matrix adhesion.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Snail family transcriptional repressor 1 (SNAIL) is a transcription factor and the gene encoding it is localized on human chromosome 20q13.13.
Physical form
Supplied in PBS with 0.09% (W/V) sodium azide
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells.
Haraguchi M
PLoS ONE, 10(7) (2015)
Biochanin A extirpates the epithelial-mesenchymal transition in a human lung cancer
Wang Yan
Experimental and Therapeutic Medicine, 2830-2836 (2018)
TP53 Mutation, Epithelial-Mesenchymal Transition, and StemlikeFeatures in Breast Cancer Subtypes
Danila Coradini
Journal of Biomedicine and Biotechnology (2013)
SNAIL transcription factor increases the motility and invasive capacity of prostate cancer cells.
Osorio LA
Molecular Medicine Reports, 13(1), 778-786 (2016)
Sharleen V Menezes et al.
Carcinogenesis, 40(6), 805-818 (2018-12-19)
The metastasis suppressor, N-myc downstream-regulated gene-1 (NDRG1), plays multifaceted roles in inhibiting oncogenic signaling and can suppress the epithelial mesenchymal transition (EMT), a key step in metastasis. In this investigation, NDRG1 inhibited the oncogenic effects of transforming growth factor-β (TGF-β)
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