SAB1309021
Anti-phospho-mouse TSC1(S387) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
生物来源
(Mouse)
偶联物
unconjugated
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
liquid
分子量
128746Da
种属反应性
mouse
技术
dot blot: 1:500
同位素/亚型
IgG
NCBI登记号
储存温度
-10 to -25°C
靶向翻译后修饰
phosphorylation (pSer387), phosphorylation (Ser387)
基因信息
mouse ... Tsc1(64930)
一般描述
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
生化/生理作用
This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S387 of mouse TSC1.
外形
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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