生物来源
(Human)
偶联物
unconjugated
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
monoclonal
表单
liquid
分子量
28303Da
种属反应性
human
技术
western blot: 1:2000
同位素/亚型
IgG2a, kappa
储存温度
-10 to -25°C
靶向翻译后修饰
unmodified, unmodified
基因信息
human ... STAT3(6774)
一般描述
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
生化/生理作用
This Stat3 antibody is generated from a mouse immunized with Stat3 recombinant protein.
外形
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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