SAB1402157
Monoclonal Anti-CRY2 antibody produced in mouse
clone 3H4, purified immunoglobulin, buffered aqueous solution
别名:
FLJ10332, HCRY2, KIAA0658, PHLL2
产品名称
Monoclonal Anti-CRY2 antibody produced in mouse, clone 3H4, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
3H4, monoclonal
form
buffered aqueous solution
mol wt
antigen ~36.12 kDa
species reactivity
human
technique(s)
capture ELISA: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CRY2(1408)
Biochem/physiol Actions
Cryptochrome circadian regulator 2 (CRY2) is involved in DNA damage checkpoint control and cell cycle progression. It maintains the circadian rhythm through a circadian feedback loop. It is also important in immune system coordination and hematologic system development. CRY2 is a potential circadian biomarker for non-Hodgkin′s lymphoma (NHL). CRY2 is linked to rapid cycling in bipolar disorder. CRY2 functions as light-sensitive magnetosensor.
General description
Cryptochrome circadian regulator 2 (CRY2) is a core circadian gene and transcriptional repressor. CRY2 gene is located on the human chromosome 11p11.2.
Immunogen
CRY2 (NP_066940.1, 141 a.a. ~ 231 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQAIISRMELPKKPVGLVTSQQMESCRAEIQENHDETYGVPSLEELGFPTEGLGPAVWQG
Sequence
VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQAIISRMELPKKPVGLVTSQQMESCRAEIQENHDETYGVPSLEELGFPTEGLGPAVWQG
Physical form
Solution in phosphate buffered saline, pH 7.4
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
CRY2 is associated with rapid cycling in bipolar disorder patients
Sjoholm LK, et al.
Testing, 5(9), e12632-e12632 (2010)
Variants in circadian genes and prostate cancer risk: a population-based study in China
Chu Lw, et al.
Prostate Cancer and Prostatic Diseases, 11(4), 342-342 (2008)
Clock-Cancer Connection in Non-Hodgkin's Lymphoma: A Genetic Association Study and Pathway Analysis of the Circadian Gene Cryptochrome 2
Hoffman AE, et al.
Cancer Research, 69(8), 3605-3613 (2009)
Human cryptochrome exhibits light-dependent magnetosensitivity
Foley LE, et al.
Nature Communications, 2, 356-356 (2011)
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