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SAB1402273

Monoclonal Anti-MMP3 antibody produced in mouse

Name: Monoclonal Anti-MMP3 antibody produced in mouse
Brand: SIGMA

clone 4C11, purified immunoglobulin, buffered aqueous solution

别名:

CHDS6, MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03455413

Conjugate:

unconjugated

Clone:

4C11, monoclonal

Application:

ELISA (c), ELISA (i), IP

Citations:

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属性

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4C11, monoclonal

form

buffered aqueous solution

mol wt

antigen ~38.21 kDa

species reactivity

human

technique(s)

capture ELISA: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable

isotype

IgG2bκ

NCBI accession no.

NM_002422

UniProt accession no.

P08254

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MMP3(4314)

说明

General description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. (provided by RefSeq)

Immunogen

MMP3 (NP_002413, 22 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
GAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVD

Physical form

Solution in phosphate buffered saline, pH 7.4

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c