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主要文件

SAB1405370

Sigma-Aldrich

Monoclonal Anti-GDF7, (C-terminal) antibody produced in mouse

clone 3C2, purified immunoglobulin, buffered aqueous solution

别名:

BMP12

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.43

生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

3C2, monoclonal

表单

buffered aqueous solution

分子量

antigen ~36.01 kDa

种属反应性

human

技术

capture ELISA: suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... GDF7(151449)

相关类别

一般描述

This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. (provided by RefSeq)

免疫原

GDF7 (NP_878248, 361 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR

生化/生理作用

As implied by their name, BMPs (bone morphogenetic proteins) promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. It also has a role in seminal vesicle development.

外形

Solution in phosphate buffered saline, pH 7.4

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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