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SAB1405370

Monoclonal Anti-GDF7, (C-terminal) antibody produced in mouse

Name: Monoclonal Anti-GDF7, (C-terminal) antibody produced in mouse
Brand: SIGMA

clone 3C2, purified immunoglobulin, buffered aqueous solution

别名:

BMP12

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关于此项目

NACRES:

NA.43

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

3C2, monoclonal

Application:

ELISA (c), ELISA (i), WB

Citations:

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属性

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3C2, monoclonal

form

buffered aqueous solution

mol wt

antigen ~36.01 kDa

species reactivity

human

technique(s)

capture ELISA: suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

isotype

IgG

NCBI accession no.

NM_182828

UniProt accession no.

Q7Z4P5

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GDF7(151449)

说明

General description

This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. (provided by RefSeq)

Immunogen

GDF7 (NP_878248, 361 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR

Biochem/physiol Actions

As implied by their name, BMPs (bone morphogenetic proteins) promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. It also has a role in seminal vesicle development.

Physical form

Solution in phosphate buffered saline, pH 7.4

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

06209-3C2

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Bone Morphogenetic Protein (BMP) signaling in development and human diseases.

Wang RN

Genes & Development, 1(1), 87-105 (2014)

全球贸易项目编号

货号	GTIN
SAB1405370-100UG	04061829632212