SAB1405562
Anti-CAT antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
别名:
MGC138422, MGC138424
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, WB
Citations:
6
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~59.8 kDa
species reactivity
human
technique(s)
indirect immunofluorescence: suitable, western blot: 1 μg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CAT(847)
General description
Catalase (CAT) is an antioxidant enzyme. CAT gene is located on human chromosome 11p13. CAT is present in peroxisomes of most aerobic organisms. It is a heme enzyme expressed mainly in liver.
Immunogen
CAT (NP_001743.1, 1 a.a. ~ 527 a.a) full-length human protein.
Sequence
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
Sequence
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
Biochem/physiol Actions
Catalase (CAT) protects different cell types from the harmful effects of hydrogen peroxide. It is involved in idiopathic male infertility. CAT converts hydrogen peroxide to water and molecular oxygen. CAT promotes resistance against many diseases. Mutations in CAT is linked to acatalasemia.
Physical form
Solution in phosphate buffered saline, pH 7.4
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Association of CAT--262C/T with the concentration of catalase in seminal plasma and the risk for male infertility in Algeria
Bousnane N, et al.
Systems Biology in Reproductive Medicine, 63(5) (2017)
Regulation of catalase expression in healthy and cancerous cells
Glorieux C, et al.
Free Radical Biology & Medicine, 87(3) (2015)
A novel catalase mutation (a GA insertion) causes the Hungarian type of acatalasemia
Goth L , et al.
Blood Cells, Molecules and Diseases, 26(2) (2000)
A new type 1 diabetes susceptibility locus containing the catalase gene (chromosome 11p13) in a Russian population
Chistiakov D, et al.
Diabetes/metabolism Research and Reviews, 20(3) (2004)
Structure and heme environment of beef liver catalase at 2.5 A resolution
Reid T, et al.
Proceedings of the National Academy of Sciences of the USA, 78(8) (1981)
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