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Merck
CN

SAB1406748

抗-SQSTM1 小鼠抗

purified immunoglobulin, buffered aqueous solution

别名:

A170, OSIL, PDB3, ZIP3, p60, p62, p62B

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, WB
Citations:
4
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~47.7 kDa

species reactivity

human

technique(s)

indirect immunofluorescence: suitable, western blot: 1 μg/mL

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SQSTM1(8878)

General description

该基因编码一种多功能蛋白,该蛋白结合泛素并调节核因子κB(NF-kB)信号通路的激活。该蛋白作为支架/接头蛋白与TNF受体相关因子6协同作用,介导NF-κB对上游信号的激活。已经针对该基因鉴定了编码相同或不同同工型的可变剪接的转录物变体。在散发性和家族性佩吉特骨病患者中发现了该基因的突变。(由RefSeq提供)

Immunogen

SQSTM1(NP_003891, 1 a.a.~ 440 a.a)全长人蛋白。

序列
MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL

Physical form

溶于pH7.4的磷酸盐缓冲盐水中的溶液

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
SAB1406748-50UG04061837217852