SAB2102031
Anti-RNF31 antibody produced in rabbit
affinity isolated antibody
别名:
Anti-FLJ10111, Anti-FLJ23501, Anti-MGC19975, Anti-Ring finger protein 31, Anti-ZIBRA
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
13
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
mol wt
120 kDa
species reactivity
rabbit, guinea pig, rat, human
packaging
pkg of 100 μL buffered aqueous solution, pkg of 50 μg lyophilized powder
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... RNF31(55072)
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Immunogen
Synthetic peptide directed towards the middle region of human RNF31
Application
Anti-RNF31 antibody produced in rabbit has been used in immunoblotting and immunoprecipitation.
Biochem/physiol Actions
PWP2 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.
Other Notes
Synthetic peptide located within the following region: SLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKL
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.
Nakazawa S
Nature Communications, 7:12547, 1-14 (2016)
SPATA2 links CYLD to the TNF-? receptor signaling complex and modulates the receptor signaling outcomes.
Wagner SA
The Embo Journal, 35(17), 1868-1884 (2016)
Structural and functional analyses of DNA-sensing and immune activation by human cGAS.
Kato K
PLoS ONE, 8(10), 1-9 (2013)
Ian R Kelsall et al.
The EMBO journal, 41(8), e109700-e109700 (2022-03-12)
HOIL-1, a component of the linear ubiquitin chain assembly complex (LUBAC), ubiquitylates serine and threonine residues in proteins by esterification. Here, we report that mice expressing an E3 ligase-inactive HOIL-1[C458S] mutant accumulate polyglucosan in brain, heart and other organs, indicating
Seshiru Nakazawa et al.
Nature communications, 7, 12547-12547 (2016-08-25)
Optineurin (OPTN) mutations cause neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and glaucoma. Although the ALS-associated E478G mutation in the UBAN domain of OPTN reportedly abolishes its NF-κB suppressive activity, the precise molecular basis in ALS pathogenesis still remains unclear.
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