SAB2106753
Anti-GOLIM4 antibody produced in rabbit
affinity isolated antibody
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
75 kDa
species reactivity
dog, rabbit, mouse, human, horse, rat, bovine, guinea pig
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GOLIM4(27333)
rat ... Golim4(310526)
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General description
Golgi internal membrane protein 4 (GOLIM4) is a golgi type II transmembrane phosphoprotein. In human chromosome, the gene GOLIM4 is located on 3q26.2.
Immunogen
The immunogen for anti-GOLIM4 antibody: synthetic peptide derected towards the C terminal of human GOLIM4
Biochem/physiol Actions
Golim4 plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi. Golim4 plays a major role in maintaining manganese homeostasis. The expression level of Golim4 is less in cancer cells. GOLIM4 is a potential oncogene, regulates cell cycle and apoptosis in neck and cancer cells.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: DPGNRQEFHEPGHQEGDPEAEADRAAAQDINPADDPNNQGEDEFEEAEQV
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Golgi integral membrane protein 4 manipulates cellular proliferation, apoptosis, and cell cycle in human head and neck cancer
Bai Y, et al.
Bioscience Reports, 38(4), BSR20180454-BSR20180454 (2018)
Mitochondrial DNA plasticity is an essential inducer of tumorigenesis
Lee WTY, et al.,
Cell death discovery, 2(9), 16016-16016 (2016)
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
Lancet Neurology, 13(9), 893-893 (2014)
Matthew L Hemming et al.
PloS one, 4(12), e8477-e8477 (2009-12-31)
Beta-site APP cleaving enzyme 1 (BACE1) is a transmembrane aspartyl protease with a lumenal active site that sheds the ectodomains of membrane proteins through juxtamembrane proteolysis. BACE1 has been studied principally for its role in Alzheimer's disease as the beta-secretase
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