SAB2500141
Anti-B7-H4 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-B7S1, Anti-B7X, Anti-B7h.5, Anti-FLJ22418
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
4
Quality Level
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat, human, canine, mouse
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... VTCN1(79679)
General description
V-set domain containing T cell activation inhibitor 1 (VTCN1), also known as B7-H4, is a co-stimulating molecule. It is part of the B7 superfamily and the gene encoding it is localized on human chromosome 1p13.1.
Immunogen
Peptide with sequence C-SKGKGNANLEYK from the internal region of the protein sequence according to NP_078902.2.
Biochem/physiol Actions
V-set domain containing T cell activation inhibitor 1 (VTCN1) has a role in T-cell mediated immune responses. It suppresses T-cell action by inhibiting cytokine secretion and the proliferation of cells. VTCN1 has a role in pancreatic cancer and it also promotes tumor immune invasion.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
ERBB3-rs2292239 as primary type 1 diabetes association locus among non-HLA genes in Chinese
Chengjun Sun
Meta Gene (2016)
MicroRNA Expression Profiling of Pancreatic Cancer Cell Line L3.6p1 Following B7-H4 Knockdown.
Qian Y
Cellular Physiology and Biochemistry (2017)
B7-H4 is a prognostic biomarker for poor survival in patients with pancreatic cancer.
Shen L
Human Pathology (2017)
MicroRNA-125b-5p modulates the inflammatory state of macrophages via targeting B7-H4.
Diao W
Biochemical and Biophysical Research Communications (2017)
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