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Merck
CN

SAB2500302

Anti-DDAH2 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

Anti-DDAHII, Anti-Dimethylarginine dimethylaminohydrolase 2, Anti-G6a, Anti-NG30

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
indirect ELISA
western blot
Species reactivity:
mouse, human, rat
Citations:
1
Technique(s):
indirect ELISA: suitable
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-DDAH2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human, rat

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... DDAH2(23564)

Application

Anti-DDAH2 antibody produced in goat is suitable for indirect ELISA and western blot applications.

Biochem/physiol Actions

DDAH2 (Dimethylarginine dimethylaminohydrolase 2) Activity partly determines the cellular concentration of methylarginine. Concentration of ADMA (asymmetrical dimethylarginine) in endothelial cells is increased on the advent of pharmacological inhibition of DDAH, which also leads to the inhibition of NO-mediated endothelium dependent relaxation of blood vessels.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

DDAH (Dimethylarginine dimethylaminohydrolase) exists as two isoforms; DDAH1, and DDAH2. Tissues expressing endothelial nitric oxide synthases is predominated by DDAH2.

Immunogen

Peptide with sequence SSLCLVLSTRPHS from the C Terminus of the protein sequence according to NP_039268.1.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J M Leiper et al.
The Biochemical journal, 343 Pt 1, 209-214 (1999-09-24)
Methylarginines inhibit nitric oxide synthases (NOS). Cellular concentrations of methylarginines are determined in part by the activity of dimethylarginine dimethylaminohydrolase (DDAH; EC 3.5.3. 18). We have cloned human DDAH and identified and expressed a second novel DDAH isoform (DDAH I

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