SAB2500485
Anti-GPX3 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Extracellular glutathione peroxidase, Anti-GPx-P, Anti-GSHPx-3, Anti-GSHPx-P, Anti-Glutathione peroxidase 3 (plasma)
产品名称
Anti-GPX3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, canine, rat, human
technique(s)
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GPX3(2878)
Application
Anti-GPX3 antibody has been used in western blotting.
Biochem/physiol Actions
Glutathione peroxidase 3 (GPX3) blocks oxidative damages by decreasing redundant reactive oxygen species (ROS). It plays a major role in solid tumors and hematological malignancies. GPX3 also plays an important role in the effectiveness of leukemic stem cells (LSCs) and self renewal actions of hematopoietic stem cells (HSCs).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Glutathione peroxidase 3 (GPX3) belongs to the glutathione peroxidase (GPX) family. It is located on human chromosome 5q23.
Immunogen
Peptide with sequence C-NQFGKQEPGENSE from the internal region of the protein sequence according to NP_002075.2.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome
J D Zhou, et al.
Cancer Medicine, 6(1), 267-274 (2017)
Relationship between proinflammatory and antioxidant proteins with the severity of cardiovascular disease in type 2 diabetes mellitus
B G Fontana, et al.
International Journal of Molecular Sciences, 16(5), 9469-9483 (2015)
Beatriz García-Fontana et al.
International journal of molecular sciences, 16(5), 9469-9483 (2015-04-30)
Type 2 diabetes mellitus patients are at significant risk of cardiovascular disease, however, the pathophysiology of these complications is complex and incompletely known in this population. The aim of this study was to compare the serum proteome of patients with
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