SAB2500652
Anti-MTHFD1 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Formyltetrahydrofolate synthetase, Anti-MTHFC, Anti-MTHFD, Anti-Methenyltetrahydrofolate cyclohydrolase, Anti-Methylenetetrahydrofolate dehydrogenase 1
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
3
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MTHFD1(4522)
General description
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) possesses 5, 10-methylenetetrahydrofolate dehydrogenase, 5, 10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase activity. The gene encoding this protein is localized on human chromosome 14q23.3.
Immunogen
Peptide with sequence RGDLNDCFIPCTPK from the internal region of the protein sequence according to NP_005947.2.
Biochem/physiol Actions
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) has a role in folate-mediated one-carbon metabolism. It is involved in the conversion of formate and tetrahydrofolate to 5, 10-methylenetetrahydrofolate.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Characterization and review of MTHFD1 deficiency: four new patients, cellular delineation and response to folic and folinic acid treatment.
Burda P
Journal of inherited metabolic disease (2015)
Genetic variation in genes involved in folate and drug metabolism in a south Indian population
Padmalatha S Rai
Indian Journal of Human Genetics (2011)
MTHFD1 regulates nuclear de novo thymidylate biosynthesis and genome stability.
Field MS
Biochimie (2016)
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