SAB2500652
Anti-MTHFD1 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Formyltetrahydrofolate synthetase, Anti-MTHFC, Anti-MTHFD, Anti-Methenyltetrahydrofolate cyclohydrolase, Anti-Methylenetetrahydrofolate dehydrogenase 1
生物来源
goat
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human, rat, mouse
技术
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MTHFD1(4522)
一般描述
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) possesses 5, 10-methylenetetrahydrofolate dehydrogenase, 5, 10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase activity. The gene encoding this protein is localized on human chromosome 14q23.3.
免疫原
Peptide with sequence RGDLNDCFIPCTPK from the internal region of the protein sequence according to NP_005947.2.
生化/生理作用
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) has a role in folate-mediated one-carbon metabolism. It is involved in the conversion of formate and tetrahydrofolate to 5, 10-methylenetetrahydrofolate.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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警示用语：
Warning
危险声明
预防措施声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Characterization and review of MTHFD1 deficiency: four new patients, cellular delineation and response to folic and folinic acid treatment.
Burda P
Journal of inherited metabolic disease (2015)
MTHFD1 regulates nuclear de novo thymidylate biosynthesis and genome stability.
Field MS
Biochimie (2016)
Genetic variation in genes involved in folate and drug metabolism in a south Indian population
Padmalatha S Rai
Indian Journal of Human Genetics (2011)
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