SAB2500652
Anti-MTHFD1 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-Formyltetrahydrofolate synthetase, Anti-MTHFC, Anti-MTHFD, Anti-Methenyltetrahydrofolate cyclohydrolase, Anti-Methylenetetrahydrofolate dehydrogenase 1
生物来源
goat
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human, rat, mouse
技术
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MTHFD1(4522)
一般描述
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) possesses 5, 10-methylenetetrahydrofolate dehydrogenase, 5, 10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase activity. The gene encoding this protein is localized on human chromosome 14q23.3.
免疫原
Peptide with sequence RGDLNDCFIPCTPK from the internal region of the protein sequence according to NP_005947.2.
生化/生理作用
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) has a role in folate-mediated one-carbon metabolism. It is involved in the conversion of formate and tetrahydrofolate to 5, 10-methylenetetrahydrofolate.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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警示用语：
Warning
危险声明
预防措施声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Characterization and review of MTHFD1 deficiency: four new patients, cellular delineation and response to folic and folinic acid treatment.
Burda P
Journal of inherited metabolic disease (2015)
Genetic variation in genes involved in folate and drug metabolism in a south Indian population
Padmalatha S Rai
Indian Journal of Human Genetics (2011)
MTHFD1 regulates nuclear de novo thymidylate biosynthesis and genome stability.
Field MS
Biochimie (2016)
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