SAB2500663
Anti-MYB/C-MYB antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-MYB, Anti-Myeloblastosis viral (v-myb) oncogene homolog, avian, Anti-c-Myb_CDS, Anti-v-myb Myeloblastosis viral oncogene homolog (avian)
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC, WB
Citations:
3
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, mouse, rat, canine
technique(s)
immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MYB(4602)
General description
Myeloblastosis (MYB) proto-oncogene, transcription factor (MYB) gene codes for a transcriptional activator, Myb-nuclear factor 1 B-type (MYB-NFIB), and is located on human chromosome 6q23.3.
Immunogen
Peptide with sequence C-QRHYNDEDPEKEKR from the internal region of the protein sequence according to NP_005366.2.
Biochem/physiol Actions
Myeloblastosis (MYB) proto-oncogene, transcription factor (MYB) plays a key role in modulating various cellular genes that participates in the proliferation, differentiation, and apoptosis of cells. This protein promotes the development and metastasis of salivary adenoid cystic carcinoma (SACC). MYB plays ah role in initiating and maintaining acute leukemias. It participates in pancreatic cancer, prostate cancer, colorectal cancer, and breast cancer (BC).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Ren-Ming Yang et al.
Oncogene, 38(26), 5239-5249 (2019-04-12)
Over 70% of human breast cancers are estrogen receptor-positive (ER+), most of which express MYB. In these and other cell types, the MYB transcription factor regulates the expression of many genes involved in cell proliferation, differentiation, tumorigenesis, and apoptosis. So
Li-Hua Xu et al.
International journal of oncology, 54(5), 1579-1590 (2019-03-22)
The incidence of recurrent t(6;9) translocation of the MYB proto‑oncogene to NFIB (the gene that encodes nuclear factor 1 B‑type) in adenoid cystic carcinoma (ACC) tumour tissues is high. However, MYB [the gene that encodes transcriptional activator Myb (MYB)] overexpression is more common
Eleni M Rettig et al.
The Laryngoscope, 125(9), E292-E299 (2015-05-13)
Salivary gland adenoid cystic carcinoma (ACC) is rare, aggressive, and challenging to treat. Many ACCs have a t(6;9) chromosomal translocation resulting in a MYB-NFIB fusion gene, but the clinical significance is unclear. The purposes of this study were to describe
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