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Merck
CN

SAB2501087

Anti-Uncoupling Protein 2/UCP2 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

Anti-SLC25A8, Anti-UCPH, Anti-Uncoupling protein 2

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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunofluorescence
indirect ELISA
western blot
Species reactivity:
mouse, rat
Citations:
5
Technique(s):
immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-Uncoupling Protein 2/UCP2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat

technique(s)

immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... UCP2(7351)

Application

Anti-uncoupling protein 2/UCP2 antibody has been used in immunoblotting.

Biochem/physiol Actions

Uncoupling protein 2 (UCP2) controls energy metabolism and decreases the production of reactive oxygen species and guards against reperfusion damage. It plays a vital role in uncoupling electron transport from adenosine triphosphate (ATP) formation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein. It expressed in various regions of the brain. In non-human primates, it is present in the hypothalamic nuclei, pituitary gland, brainstem, ventral tegmental area and substantia nigra. It is located on human chromosome 11q13.

Immunogen

Peptide with sequence C-DSVKQFYTKGSEH from the internal region of the protein sequence according to NP_003346.2.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Uncoupling protein 2 haplotype does not affect human brain structure and function in a sample of community-dwelling older adults
Heise, et al.
PLoS ONE, 12(8), e0181392-e0181392 (2017)
The UCP2-866G/A Polymorphism Could be Considered as a Genetic Marker of Different Functional Prognosis in Ischemic Stroke After Recanalization
Cicuendez I D M, et al.
Neuromolecular Medicine, 19(4), 571-578 (2017)
Uncoupling protein 2 region on chromosome 11q13 is not linked to markers of obesity in familial type 2 diabetes
Elbein S C, et al.
Diabetes, 46(12), 2105-2108 (1997)
Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto (mito) phagy markers
Marques A I, et al.
Neuroscience, 301(8), 480-495 (2015)
Jelena Stevanović-Silva et al.
Metabolism: clinical and experimental, 116, 154704-154704 (2021-01-10)
Maternal high-caloric nutrition and related gestational diabetes mellitus (GDM) are associated with a high-risk for developing metabolic complications later in life and in their offspring. In contrast, exercise is recognized as a non-pharmacological strategy against metabolic dysfunctions associated to lifestyle

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