SAB2501133
Anti-FEM1A (C-terminal) antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-DKFZp762M136, Anti-EPRAP, fem-1 homolog a (C. elegans)
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
3
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, bovine, canine
technique(s)
indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... FEM1A(55527)
General description
Fem-1 homolog A (FEM1A) is a homolog of the Fem-1 gene of Caenorhabditis elegans. It is predicted to encode an ankyrin repeat proteins which is expressed in many tissues. FEM1A is a conserved VHL-box protein. The gene encoding it is localized on human chromosome 19p13.3.
Immunogen
Peptide with sequence CGFIPEDLEAFIELH, from the C Terminus of the protein sequence according to NP_061178.1.
Biochem/physiol Actions
Fem-1 homolog A (FEM1A) is a substrate recognition subunit of cullin-2-RING E3 ubiquitin ligase complex. It has a role in the degradation of stem-loop binding protein (SLBP) and may be involved in anti-inflammatory signaling. FEM1A has been associated with polycystic ovary syndrome.
Features and Benefits
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Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
FEM1A and FEM1B: novel candidate genes for polycystic ovary syndrome.
Goodarzi MO
Human Reproduction (2008)
FEM1 proteins are ancient regulators of SLBP degradation.
Dankert JF
Cell Cycle (2017)
The Fem1c genes: conserved members of the Fem1 gene family in vertebrates.
Ventura-Holman
Gene (2003)
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