Anti-SUMF1 antibody produced in goat

Sulfatase modifying factor 1 (SUMF1) or formylglycine-generating enzyme (FGE) is a 41kDa glycoprotein. It is localized at the lumen of the endoplasmic reticulum. The protein consists of an amino-terminal domain and a core domain with the active site. The gene encoding SUMF1 is localized on human chromosome 3p26.1 and contains nine exons.

Peptide with sequence CETLNPKGPPSGKDR, from the internal region of the protein sequence according to NP_877437.2.

Sulfatase modifying factor 1 (SUMF1) converts a highly conserved cysteine in the catalytic domain of sulfatase to form C α-formylglycine (FGly) by post-translational modification. Mutations in the gene encoding this protein have been associated with multiple sulfatase deficiency.

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Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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