SAB2501537
Anti-GNB3 antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
G protein, beta-3 subunit, GTP-binding regulatory protein beta-3 chain, Guanine nucleotide binding protein (G protein), beta polypeptide 3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC, WB
Citations:
5
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GNB3(2784)
General description
The guanine nucleotide binding protein β3 (GNB3) gene is composed of 11 exons and 10 introns. It is the 3 subunit of heterotrimeric G-proteins located on human chromosome 12p13.
Immunogen
Peptide with sequence SGHDNRVSCLGVT, from the internal region of the protein sequence according to NP_002066.1, NP_067642.1
Biochem/physiol Actions
Guanine nucleotide binding protein 3 (GNB3) is involved in the conversion of external receptor activation signals into intracellular signals and it plays an important role in signal transduction pathways. It modulates and associates with favorable antidepressant response. GNB3 takes part in a variety of cellular processes like G protein-coupled receptor signaling.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
G protein beta 3 gene: structure, promoter, and additional polymorphisms
Rosskopf, D
Hypertension (2000)
The cationic region of Rhes mediates its interactions with specific Gbeta subunits
Hill C
Journal of advanced nursing null
Studies of the association of the GNB3825C>T polymorphism with components of the
metabolic syndrome in white
metabolic syndrome in white
Danes G. Andersen
Journal of AOAC (Association of Official Analytical Chemists) International null
Suggestive association between the C825T polymorphism of the G-protein ?3 subunit gene
(GNB3) and clinical improvement with antipsychotics in schizophrenia
(GNB3) and clinical improvement with antipsychotics in schizophrenia
Daniel J. Mullerag
Journal of advanced nursing null
Association of a human G-protein beta3 subunit variant with hypertension
Siffert W
Journal of AAPOS : The Official Publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus null
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